Histidine-rich glycoprotein plus zinc reverses growth inhibition of vascular smooth muscle cells by heparin


Vascular smooth muscle cell (SMC) hyperplasia is known to be an important component in the pathogenesis of arteriosclerosis and restenosis. Although heparin has been well recognized as the representative molecule suppressing SMC growth in vitro, attempts to use heparin as a therapeutic anti-restenosis drug have not favorably influenced the angiographic or… (More)
DOI: 10.1007/s00441-003-0737-x


5 Figures and Tables