Histidine-rich glycoprotein modulates the anti-angiogenic effects of vasculostatin.

Abstract

Brain angiogenesis inhibitor 1 (BAI1) is a transmembrane protein expressed on glial cells within the brain. Its expression is dramatically down-regulated in many glioblastomas, consistent with its functional ability to inhibit angiogenesis and tumor growth in vivo. We have shown that the soluble anti-angiogenic domain of BAI1 (termed Vstat120) requires CD36… (More)
DOI: 10.2353/ajpath.2010.090782

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