Histamine2-receptor antagonists are an alternative to proton pump inhibitor in patients receiving clopidogrel.

  title={Histamine2-receptor antagonists are an alternative to proton pump inhibitor in patients receiving clopidogrel.},
  author={C Y Wu and Francis Ka-leung Chan and Ming-Shiang Wu and Ken N. Kuo and C Wang and Chen-Rong Tsao and Jaw-town Lin},
  volume={139 4},
BACKGROUND & AIMS Previous observational studies reported that concomitant use of clopidogrel and proton pump inhibitors (PPIs) in patients with prior acute coronary syndrome (ACS) was associated with adverse cardiovascular outcomes. We investigated whether H(2)-receptor antagonist (H(2)RA) is an alternative to PPI in patients with ACS. METHODS We conducted a population-based retrospective cohort study of 6552 patients in Taiwan discharged for ACS between 2002 and 2005. Patients were divided… CONTINUE READING

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