Histamine uptake and metabolism in intact isolated parietal cells

Abstract

3H-Histamine binding, uptake and metabolism were investigated in intact isolated and enriched parietal cells from the dog and guinea pig. Histamine uptake was sodium dependent and followed by intracellular metabolism. The only metabolite that was detected and extracted from cytosol has been identified by TLC to beN r-methylhistamine. The histamineN… (More)
DOI: 10.1007/BF01967618

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