Histamine release from the cultured mouse mast cell line PT 18 in response to immunologic and non-immunologic stimuli

@article{Barrett1984HistamineRF,
  title={Histamine release from the cultured mouse mast cell line PT 18 in response to immunologic and non-immunologic stimuli},
  author={Kim E Barrett and Dov H. Pluznik and Dean D Metcalfe},
  journal={Agents and Actions},
  year={1984},
  volume={14},
  pages={488-493}
}
Cultured mouse mast cells that are dependent on spleen-derived factors for their proliferation and maintenance have been shown rapidly to release histamine in response to immunologic stimuli, concanavalin A, and ionophores A23187 and Br-x537A. These cells did not, however, release histamine when treated with compound 48/80 or adenosine 5′-triphosphate… CONTINUE READING