Histamine release from mast cells by polyamines: an NMDA receptor-mediated event?


In recent years it has become apparent that the role of the mast cell is not confined to immediate hypersensitivity reactions and that the cell may participate in a range of nonIgE mediated processes. The natural polyamines induce histamine release from rat peritoneal mast cells (RPMC) in a concentrationand energy-dependent process with a rank order of… (More)