Histamine regulation of biliary proliferation.

  title={Histamine regulation of biliary proliferation.},
  author={Heather Francis and Fanyin Meng and Eugenio Gaudio and Gianfranco D. Alpini},
  journal={Journal of hepatology},
  volume={56 5},
Cholangiocytes, which line the biliary epithelium, are hormoneresponsive and responsible for the modification of canalicular bile before reaching the duodenum. Cholangiocytes are the target cells in cholangiopathies such as primary biliary cirrhosis (PBC) and primary sclerosing cholangitis (PSC) that are characterized by cholangiocyte proliferation/loss [1… CONTINUE READING