Histamine receptor H1 in the nucleus tractus solitarii regulates arterial pressure and heart rate in rats.

@article{Bhuiyan2011HistamineRH,
  title={Histamine receptor H1 in the nucleus tractus solitarii regulates arterial pressure and heart rate in rats.},
  author={Mohammad Eliusur Rahman Bhuiyan and H. Waki and Sabine S S Gouraud and Miwa Takagishi and Akira Kohsaka and Masanobu Maeda},
  journal={American journal of physiology. Heart and circulatory physiology},
  year={2011},
  volume={301 2},
  pages={H523-9}
}
Axons of histamine (HA)-containing neurons are known to project from the posterior hypothalamus to many areas of the brain, including the nucleus tractus solitarii (NTS), a central brain structure that plays an important role in regulating arterial pressure. However, the functional significance of NTS HA is still not fully established. In this study, we microinjected HA or 2-pyridylethylamine, a HA-receptor H(1)-specific agonist, into the NTS of urethane-anesthetized Wister rats to identify the… CONTINUE READING

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