Histamine provocation in young, awake children with bronchial asthma, using a fall in oxygenation as the only indicator of a bronchial reaction.

@article{Holmgren1999HistaminePI,
  title={Histamine provocation in young, awake children with bronchial asthma, using a fall in oxygenation as the only indicator of a bronchial reaction.},
  author={Daniel Holmgren and Staffan B Redfors and G{\"o}ran Wennergren and Gunilla M Sten},
  journal={Acta paediatrica},
  year={1999},
  volume={88 5},
  pages={545-9}
}
Bronchial provocation with histamine was performed in 11 boys and 6 girls, age range 2.7-7.4 y, with unspecific respiratory symptoms or bronchial asthma, using a fall in oxygenation as the only indicator of a bronchial reaction. In addition to transcutaneous oxygen tension (tcPO2), transcutaneous carbon dioxide tension (tcPCO2) was continuously monitored during the provocation procedure in order to identify possible changes in ventilation. A fall of 20% or more in the tcPO2 below a "floating… CONTINUE READING