Histamine metabolism in the Arthus reaction.

  title={Histamine metabolism in the Arthus reaction.},
  author={Takao Tachibana and Shinkichi Taniguchi and Fukiko Furukawa and S. I. hiro Imamura},
  journal={Experimental and molecular pathology},
  volume={44 1},
Histamine metabolism, i.e., concentration of histamine and activities of histamine-degrading enzymes, histamine-N-methyltransferase (HMT), and diamine oxidase (DAO), were examined in the Arthus reaction induced in guinea pig skin. The specific activity of HMT was 44.12 +/- 3.80 pmole/min/mg protein and was about 15 times greater than that of DAO in control specimens. However, HMT activity decreased time dependently to 35% of the control at 3 hr and to 10% 48 hr after the initiation of the… CONTINUE READING

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