Histamine metabolism in mastocytosis patients treated with interferon α-2b

Recently, Kluin-Nelemans and co-workers [1] reported the successful treatment of one patient with an "aggressive systemic mastocytosis" with interferon a-2b (INF-a). The patient was a 42 year old man with urticaria pigmentosa and progressive mast cell infiltration of the bone marrow, liver and spleen accompanied with ascites, and with an exceptionally high… (More)