Histamine-mediated delayed permeability response after scald burn inhibited by cimetidine or cold-water treatment.

@article{Boykin1980HistaminemediatedDP,
  title={Histamine-mediated delayed permeability response after scald burn inhibited by cimetidine or cold-water treatment.},
  author={J V Boykin and Elof Eriksson and Milton M. Sholley and Roland N Pittman},
  journal={Science},
  year={1980},
  volume={209 4458},
  pages={
          815-7
        }
}
Scald injury to one ear of the hairless mouse induced significant (P < .05) delayed edema formation in remote, uninjured skin. This remote edema formation was completely inhibited by immediate cold-water treatment of the scalded ear. Cold-water treatment significantly reduced histamine loss from the scalded ear, and the edema-inhibiting effect of the treatment could be mimicked by treating the animal prior to injury with the H2-histamine receptor antagonist cimetidine or a drug that causes… 
View on PubMed
science.sciencemag.org
43 Citations
Background Citations
2
Methods Citations
1

43 Citations

Citation Type

Citation Type

Cold-water treatment of scald injury and inhibition of histamine-mediated burn edema.
Mechanisms of cimetidine protection following thermal injury.
The effect of prompt local cooling on oedema formation in scalded rat paws.
Effect of cold water immersion on oedema formation in the scalded mouse ear.
Role of histamine receptors in the regulation of edema and circulation postburn.
Effects of hyperbaric oxygen on oedema formation after a scald burn.
Urinary excretion of histamine and methylhistamine after burns.
The effect of different cooling temperatures and immersion fluids on post-burn oedema and survival of the partially scalded hairy mouse ear.
Effects of amide local anaesthetics on eicosanoid formation in burned skin
TLDR
The effects of topical lidocaine/prilocaine cream and intravenous lidocane with that of saline on eicosanoid formation by normal and burned rat skin are compared.
Topical local anaesthetics (EMLA) inhibit burn-induced plasma extravasation as measured by digital image colour analysis.
...
1
2
3
4
5
...

References

SHOWING 1-8 OF 8 REFERENCES
Time course of histamine release and edema formation in the rat paw after thermal injury.
Microvascular ultrastructure in thermal injury: a reconsideration of the role of mediators.
Quantitative morphological correlations of alterations in capillary permeability, following histamine and moderate burning, in the mouse diaphragm; and the effects of benzopyrones.
Inhibition of the release of histamine from rat mast cells: the effect of cold and adrenergic drugs on release of histamine by compound 48-80 and antigen.
  • A. Johnson, N. Moran
  • Biology, Medicine
    The Journal of pharmacology and experimental therapeutics
  • 1970
TLDR
The inhibition by drugs of the selective histamine releasing agents, antigen and 48/80, could be related to any known adrenergic mechanisms but release of histamine by Triton X-100 was not inhibited by any of the drugs tested.
A study of possible mediators of inflammatory reactions in the mouse foot.
TLDR
An attempt has been made to elucidate the ways in which certain hydroxybenzoates, pyrazolones, sympathomimetic amines, flavone and flavanone glycosides, local anaesthetics, antihistamines and anti-5-hydroxytryptamine substances produce their anti-inflammatory effect.
The passage of macromolecules across inflamed capillary endothelium via large vacuoles.
Studies on histamine release from skin and from peritoneal mast cells of the rat induced by heat.
Vascular permeability changes in inflammation: the role of endogenous permeability factors in mild thermal injury.