Histamine is a powerful stimulator of cyclic AMP formation in chick pineal gland

@article{Nowak1994HistamineIA,
  title={Histamine is a powerful stimulator of cyclic AMP formation in chick pineal gland},
  author={Jerzy Zygmunt Nowak and B. Sek},
  journal={Agents and Actions},
  year={1994},
  volume={41},
  pages={C60-C61}
}
Histamine (HA) potently stimulated both basal and forskolin-activated cAMP formation in chick pineal gland. The action of HA was mimicked by 4-methyl-HA, and to some extent by 2-methyl-HA and 2-thiazolylethylamine (2TEA), but not by dimaprit, (R)-α-methyl-HAtele-methyl-HA, and several other imidazole-derivatives. The stimulatory actions of all the compounds were antagonized by ranitidine and tiotidine (HA H2-receptor antagonists), and were not affected by mepyramine and thioperamide (HA H1- and… CONTINUE READING

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Showing 1-7 of 7 references

The effect of histamine H1- and Ha-receptor antagonists on histamine-stimulated cAMP accumulation in chick cerebral cortical slices

  • J. M. Brine, C. R. Calcutt, F. Nilam, L A. Poat, I. R. Smith, G. N. Woodruff
  • Br. J. Pharmacol~ 80,
  • 1983
2 Excerpts

Creveling, A radioisotopic method for measuring the formation of adenosine 3',5'-cyelic monophosphate in incubated slices of brain

  • H. Shimizu, jr, C.R.W. Daly
  • J. Neurochem
  • 1969
1 Excerpt

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