Histamine inhibits advanced glycation end products-induced adhesion molecule expression on human monocytes.


Advanced glycation end products (AGEs) are modifications of proteins/lipids that become nonenzymatically glycated after contact with aldose sugars. Among various subtypes of AGEs, glyceraldehyde-derived AGE (AGE-2) and glycolaldehyde-derived AGE (AGE-3) are suggested to play roles in inflammation in diabetic patients. Because the engagement of intercellular… (More)
DOI: 10.1124/jpet.109.155960


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