Histamine induces oscillations of mitochondrial free Ca2+ concentration in single cultured rat brain astrocytes.

Abstract

1. The free Ca2+ concentration of mitochondria ([Ca2+]m) in cultured rat brain astrocytes was measured with a fluorescent Ca2+ indicator, rhod-2, and laser confocal microscopy. 2. Confocal images revealed a rhod-2 distribution that matched mitochondrial localization. 3. Using a Ca2+ ionophore, ionomycin, to clamp the [Ca2+]m from 0 to 100 microM in order to… (More)

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@article{Jou1996HistamineIO, title={Histamine induces oscillations of mitochondrial free Ca2+ concentration in single cultured rat brain astrocytes.}, author={M. J. Jou and Tai-Quan Peng and S. S. Sheu}, journal={The Journal of physiology}, year={1996}, volume={497 ( Pt 2)}, pages={299-308} }