Histamine-induced modulation of vascular tone in the isolated chicken basilar artery: a possible involvement of endothelium.

We investigated the histamine responsiveness of basilar arterial rings isolated from chicken. We also examined whether endothelial cells were involved in the histamine responsiveness and in resting vascular tone. Histamine induced concentration-dependent relaxations under condition of precontraction by 5-hydroxytryptamine. The concentration-response curve… CONTINUE READING