Histamine-induced asthma in children: effects on the ventilation-perfusion relationship.

Asthma was provoked by histamine inhalation in five children in order to study the hypoxaemia that might ensue and the underlying ventilation-perfusion (VA/Q) mismatching. The distribution of the VA/Q ratios was measured by a multiple inert gas technique before the provocation, during the asthmatic attack and after salbutamol inhalation. All children… CONTINUE READING