Histamine increases the level of IFNγ produced by HIV-1 specific CTLs and this production depends on total IgE level.

@article{Hanzlkov2012HistamineIT,
  title={Histamine increases the level of IFNγ produced by HIV-1 specific CTLs and this production depends on total IgE level.},
  author={Jana Hanzl{\'i}kov{\'a} and Dalibor Sedl{\'a}{\vc}ek and Miroslav Liska and Jitka Gorcikova and Tom{\'a}{\vs} Vlas and S Amiramini and Petr Panzner and Marek Mal{\'y}},
  journal={Journal of immunological methods},
  year={2012},
  volume={375 1-2},
  pages={1-6}
}
BACKGROUND The HIV (human immunodeficiency virus) population remains a global concern whose treatment is effective, though not yet optimal. Immune based therapies have thus far been disappointing and still need to be explored further. Based on published data suggesting that the functions of cytotoxic CD8+ T lymphocytes (CTL) can be improved by histamine, we investigated the effect of histamine in vitro on HIV-1 specific CD8+ T lymphocytes in HIV+ subjects. RESULTS 60 HIV+ subjects were… CONTINUE READING