Histamine in two component system-mediated bacterial signaling.

  title={Histamine in two component system-mediated bacterial signaling.},
  author={Dimitrios A. Kyriakidis and Marina C. Theodorou and Ekaterini Tiligada},
  journal={Frontiers in bioscience},
Histamine is a key mediator governing vital cellular processes in mammals beyond its decisive role in inflammation. Recent evidence implies additional actions in both eukaryotes and prokaryotes. Besides its function in host defense against bacterial infections, histamine elicits largely undefined actions in microorganisms that may contribute to bacteria-host interactions. Bacterial proliferation and adaptation are governed by sophisticated signal transduction networks, including the versatile… 

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