Histamine function in brain disorders.

  title={Histamine function in brain disorders.},
  author={Luc{\'i}a Fern{\'a}ndez-Novoa and Ram{\'o}n Cacabelos},
  journal={Behavioural brain research},
  volume={124 2},
The neurotransmitter histamine (HA) has been implicated in the regulation of numerous and important activities of the central nervous system as arousal, cognition, circadian rhythms and neuroendocrine regulation. The data presented here indicate the participation of the histaminergic system in central nervous system disorders, such as Alzheimer's disease and schizophrenia. We also present experimental data on histamine in an animal model of neurodegeneration and the cytotoxic effects of… CONTINUE READING