Histamine-containing peripheral neuronal and endocrine systems.

  title={Histamine-containing peripheral neuronal and endocrine systems.},
  author={Pertti Panula and Maija A Kaartinen and M M{\"a}cklin and Erminio Costa},
  journal={The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society},
  volume={33 9},
An immunohistochemical method was developed to detect histamine in tissues. The aim of this study was to reveal the cellular stores of histamine in the gastrointestinal tract, pituitary, and adrenal gland. Histamine-containing nerve fibers were found in both rat and guinea pig gut. The origin of at least some of these fibers in the rat ileum was the submucous ganglion cell layer. In the rat stomach, numerous enterochromaffin-like cells exhibited histamine immunofluorescence, and endocrine cells… CONTINUE READING