Histamine-2 receptor blockers alter the fecal microbiota in premature infants.

  title={Histamine-2 receptor blockers alter the fecal microbiota in premature infants.},
  author={Raegan W Gupta and Lynn E Tran and Johana Norori and Michael J. Ferris and A. Murat Eren and Christopher M Taylor and Scot E. Dowd and Duna Penn},
  journal={Journal of pediatric gastroenterology and nutrition},
  volume={56 4},
OBJECTIVES Bacterial colonization is considered a major risk factor for necrotizing enterocolitis (NEC). The objective of the present study was to test the hypothesis that histamine-2 receptor (H2-) blockers alter colonic bacterial colonization by analyzing and comparing the fecal microbiota in premature infants with and without H2-blocker therapy using sensitive molecular biological techniques. METHODS Seventy-six premature infants ≤1500 g or <34 weeks gestation were enrolled in this case… CONTINUE READING
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