Histamine: A mediator of inflammation.

  title={Histamine: A mediator of inflammation.},
  author={Donald W Macglashan},
  journal={The Journal of allergy and clinical immunology},
  volume={112 4 Suppl},
Histamine and its receptors, including the recently discovered receptors (H(3) and H(4)), novel sources of histamine, and the place of histamine in mediator networks continue to be areas of great interest. The 4 major subtypes of histamine receptors, H(1) to H(4), differ in their location, second messengers, and histamine-binding characteristics. In addition, it would appear that different histamine receptor agonists and antagonists bind to different portions of the receptor complex. A fifth… CONTINUE READING


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