Hippocampus of the seizure-sensitive gerbil is a specific site for anatomical changes in the GABAergic system.

@article{Peterson1987HippocampusOT,
  title={Hippocampus of the seizure-sensitive gerbil is a specific site for anatomical changes in the GABAergic system.},
  author={Gary M. Peterson and Charles E. Ribak},
  journal={The Journal of comparative neurology},
  year={1987},
  volume={261 3},
  pages={405-22}
}
The brains of seizure-sensitive (SS) and seizure-resistant (SR) gerbils were studied with an immunocytochemical method to localize glutamic acid decarboxylase (GAD) to determine whether a defect existed in the inhibitory GABAergic system similar to that which has been reported in animal models of focal epilepsy in which GABAergic cell bodies and terminals are decreased in number. A major difference between the two strains of gerbils was found in the number of GABAergic neurons in the… CONTINUE READING

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