Hippocampal volume deficits associated with exposure to psychological trauma and posttraumatic stress disorder in adults: A meta-analysis
@article{Woon2010HippocampalVD, title={Hippocampal volume deficits associated with exposure to psychological trauma and posttraumatic stress disorder in adults: A meta-analysis}, author={Fu Lye M Woon and Shabnam Sood and Dawson W. Hedges}, journal={Progress in Neuro-Psychopharmacology and Biological Psychiatry}, year={2010}, volume={34}, pages={1181-1188} }
326 Citations
Smaller hippocampal volume as a vulnerability factor for the persistence of post-traumatic stress disorder
- Psychology, BiologyPsychological Medicine
- 2015
It is demonstrated for the first time that a smaller (left) hippocampus constitutes a risk factor for the persistence of PTSD.
Volume and shape analysis of the Hippocampus and amygdala in veterans with traumatic brain injury and posttraumatic stress disorder
- Psychology, BiologyBrain Imaging and Behavior
- 2019
The results suggest that the amygdala may be a neuroanatomical correlate in mediating PTSD-like symptoms in Veterans with TBI and alterations in the CA1 and subiculum subregions of hippocampus may have a role in depression and PTSD.
Alcohol use and hippocampal volume deficits in adults with posttraumatic stress disorder: A meta-analysis
- Psychology, BiologyBiological Psychology
- 2010
Grey matter reduction associated with posttraumatic stress disorder and traumatic stress
- Psychology, BiologyNeuroscience & Biobehavioral Reviews
- 2014
Post-traumatic stress symptoms correlate with smaller subgenual cingulate, caudate, and insula volumes in unmedicated combat veterans
- PsychologyPsychiatry Research: Neuroimaging
- 2012
Decreased left hippocampal volumes in parents with or without posttraumatic stress disorder who lost their only child in China.
- Psychology, BiologyJournal of affective disorders
- 2016
Hippocampal and amygdala volumes in adults with posttraumatic stress disorder secondary to childhood abuse or maltreatment: A systematic review
- Psychology, BiologyPsychiatry Research: Neuroimaging
- 2016
Amygdala volume changes in posttraumatic stress disorder in a large case-controlled veterans group.
- Psychology, BiologyArchives of general psychiatry
- 2012
These results provide clear evidence of an association between a smaller amygdala volume and PTSD, and may trigger a renewed impetus for investigating structural differences in the amygdala, its genetic determinants, its environmental modulators, and the possibility that it reflects an intrinsic vulnerability to PTSD.
Does Hippocampal Volume in Patients with Posttraumatic Stress Disorder Vary by Trauma Type?
- Psychology, BiologyHarvard review of psychiatry
- 2022
Mixed-effects meta-analyses suggest that trauma type may moderate hippocampal volume in trauma-exposed individuals but not in those with PTSD.
Evidence for smaller right amygdala volumes in posttraumatic stress disorder following childhood trauma
- Psychology, BiologyPsychiatry Research: Neuroimaging
- 2015
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In monozygotic twins discordant for trauma exposure, it is found evidence that smaller hippocampi indeed constitute a risk factor for the development of stress-related psychopathology.
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Alcohol use and hippocampal volume deficits in adults with posttraumatic stress disorder: A meta-analysis
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