Hippocampal volume deficits and shape deformities in young biological relatives of schizophrenia probands

@article{Ho2010HippocampalVD,
  title={Hippocampal volume deficits and shape deformities in young biological relatives of schizophrenia probands},
  author={Beng-Choon Ho and Vincent Magnotta},
  journal={NeuroImage},
  year={2010},
  volume={49 4},
  pages={3385-93}
}
Hippocampal volume decrement may be one of the changes that most closely pre-date schizophrenia onset. Studying hippocampal developmental morphology in adolescent or young adult biological relatives of schizophrenia probands has the potential to further our understanding of the neurodevelopmental etiology of schizophrenia and to discover biomarkers that may aid its early identification. We utilized an artificial neural network segmentation algorithm to automatically define and reliably measure… CONTINUE READING