Hippocampal to pituitary volume ratio: a specific measure of reciprocal neuroendocrine alterations in alcohol dependence.

@article{Beresford1999HippocampalTP,
  title={Hippocampal to pituitary volume ratio: a specific measure of reciprocal neuroendocrine alterations in alcohol dependence.},
  author={Thomas P. Beresford and David B. Arciniegas and Donald C. Rojas and Jeanelle Leigh Sheeder and Peter Teale and R Aasal and Elliot J. Sandberg and Martin Reite},
  journal={Journal of studies on alcohol},
  year={1999},
  volume={60 5},
  pages={586-8}
}
OBJECTIVE Studies to date provide conflicting views of the relationship between corticosteroids and decreased hippocampal volume in alcoholism. If this were mediated through the hypothalamic-pituitary-adrenal (HPA) axis, enlarged pituitary volumes relative to hippocampal volumes might be expected and be measurable using the hippocampus to pituitary volume (H:P) ratio. METHOD Using magnetic resonance imaging (MRI), we performed volumetric analysis of the pituitary and hippocampus on 10… CONTINUE READING

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