Hippocampal shape deformity analysis in obsessive–compulsive disorder

  title={Hippocampal shape deformity analysis in obsessive–compulsive disorder},
  author={Soon-beom Hong and Yong-Wook Shin and Sun Hyung Kim and So Young Yoo and Jong-Min Lee and In Young Kim and Sun Il Kim and PhD Jun Soo Kwon},
  journal={European Archives of Psychiatry and Clinical Neuroscience},
Abnormalities of orbital prefrontal cortex and caudate nuclei have, thus far, been the main findings regarding the pathophysiology of obsessive–compulsive disorder (OCD). On the other hand, neuroimaging studies have failed to reach a consensus with regard to the issue of hippocampal abnormalities in OCD patients. Shape analysis may facilitate a resolution of the discordance among these former studies by detecting local structural changes, thus enhancing power to discriminate structural… CONTINUE READING
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