Hippocampal sequence-encoding driven by a cortical multi-item working memory buffer

@article{Jensen2005HippocampalSD,
  title={Hippocampal sequence-encoding driven by a cortical multi-item working memory buffer},
  author={Ole Jensen and John E. Lisman},
  journal={Trends in Neurosciences},
  year={2005},
  volume={28},
  pages={67-72}
}
Encoding and recall of memory sequences is an important process. Memory encoding is thought to occur by long-term potentiation (LTP) in the hippocampus; however, it remains unclear how LTP, which has a time window for induction of approximately 100 ms, could encode the linkage between sequential items that arrive with a temporal separation >100 ms. Here, we argue that LTP can underlie the learning of such memory sequences, provided the input to the hippocampus is from a cortical multi-item… Expand
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