Hippocampal polyamine levels and transglutaminase activity are paralleling spatial memory retrieval in the C57BL/6J mouse.

@article{Tiboldi2012HippocampalPL,
  title={Hippocampal polyamine levels and transglutaminase activity are paralleling spatial memory retrieval in the C57BL/6J mouse.},
  author={Akos Tiboldi and Alessandro Lentini and Bruno Provenzano and Claudio Tabolacci and H. Hoeger and Simone Beninati and Gert Lubec},
  journal={Hippocampus},
  year={2012},
  volume={22 5},
  pages={1068-74}
}
Although a potential role for polyamines and transglutaminases (TGs) in memory mechanisms have been proposed, hippocampal spermine (SPM) and spermidine (SPD) levels as well as transamidating activity of TG in spatial memory have not been addressed yet. It was therefore the aim of the study to assess hippocampal polyamines and TG activity at the probe trial in a spatial memory paradigm. C57BL/6J mice (20 animals per group) were used for the experiments and divided into a trained and a yoked… CONTINUE READING

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Transglutaminases: nature's biological glues.

The Biochemical journal • 2002
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Highly Influenced

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