Hippocampal neuron number in schizophrenia. A stereological study.

  title={Hippocampal neuron number in schizophrenia. A stereological study.},
  author={Stephan Heckers and Helmut Heinsen and Benjamin Geiger and Helmut Beckmann},
  journal={Archives of general psychiatry},
  volume={48 11},
Neuropathologic and neuroradiologic studies have reported hippocampal abnormalities in schizophrenics. We estimated the total number of neurons in the hippocampus of schizophrenics and controls to elucidate the neuronal basis of such changes. Thirteen brains of schizophrenics and 13 control brains closely matched for sex and age were studied. A new stereological method was applied to serial coronal sections through the whole hippocampus. Total hippocampal volume was reduced in the schizophrenic… CONTINUE READING

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