Hippocampal neuroligin-2 links early-life stress with impaired social recognition and increased aggression in adult mice.

@article{Kohl2015HippocampalNL,
  title={Hippocampal neuroligin-2 links early-life stress with impaired social recognition and increased aggression in adult mice.},
  author={Christine Kohl and Xiao-Dong Wang and Jocelyn Grosse and C{\'e}line Fournier and Daniela Harbich and S{\"o}ren Westerholz and J Li and Alexandre Bacq and Claudia Sippel and Felix Hausch and Carmen Sandi and Mathias V Schmidt},
  journal={Psychoneuroendocrinology},
  year={2015},
  volume={55},
  pages={128-43}
}
Early-life stress is a key risk factor for the development of neuropsychiatric disorders later in life. Neuronal cell adhesion molecules have been strongly implicated in the pathophysiology of psychiatric disorders and in modulating social behaviors associated with these diseases. Neuroligin-2 is a synaptic cell adhesion molecule, located at the postsynaptic membrane of inhibitory GABAergic synapses, and is involved in synaptic stabilization and maturation. Alterations in neuroligin-2… CONTINUE READING
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