Hippocampal neurogenesis: Opposing effects of stress and antidepressant treatment

@article{WarnerSchmidt2006HippocampalNO,
  title={Hippocampal neurogenesis: Opposing effects of stress and antidepressant treatment},
  author={Jennifer L. Warner-Schmidt and Ronald S. Duman},
  journal={Hippocampus},
  year={2006},
  volume={16}
}
The hippocampus is one of several limbic brain structures implicated in the pathophysiology and treatment of mood disorders. Preclinical and clinical studies demonstrate that stress and depression lead to reductions of the total volume of this structure and atrophy and loss of neurons in the adult hippocampus. One of the cellular mechanisms that could account for alterations of hippocampal structure as well as function is the regulation of adult neurogenesis. Stress exerts a profound effect on… 
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