Hippocampal mossy fibre terminal field size is differentially affected in a rat model of risk-taking behaviour

@article{Isgor2004HippocampalMF,
  title={Hippocampal mossy fibre terminal field size is differentially affected in a rat model of risk-taking behaviour},
  author={Ceylan Isgor and Lutz Slomianka and Stanley J. Watson},
  journal={Behavioural Brain Research},
  year={2004},
  volume={153},
  pages={7-14}
}
Individual differences in novelty-induced exploratory activity identify rats which can serve as a model of human sensation-seeking, risk-taking behaviour. Experimentally naïve rats, when exposed to mild stress of a novel environment, exhibit variability in their exploratory activity. Some rats display high rates of locomotor reactivity to novelty (high responders (HR)), and others display low rates (low responders (LR)). The LRHR phenotype is a reliable predictor of drug-taking behaviour and is… CONTINUE READING

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