Hippocampal morphology and distinguishing late-onset from early-onset elderly depression.

  title={Hippocampal morphology and distinguishing late-onset from early-onset elderly depression.},
  author={Martina Ballmaier and Katherine Narr and Arthur W. Toga and Virginia Elderkin-Thompson and Paul M. Thompson and Liberty S. Hamilton and Ebrahim Haroon and Daniel Pham and Andreas Heinz and Anand Kumar},
  journal={The American journal of psychiatry},
  volume={165 2},
OBJECTIVE Despite evidence for hippocampal abnormalities in elderly depression, it is unknown whether these changes are regionally specific. This study used three-dimensional mapping techniques to identify regional hippocampal abnormalities in early- and late-onset depression. Neuropsychological correlates of hippocampal morphology were also investigated. METHOD With high-resolution magnetic resonance imaging, hippocampal morphology was compared among elderly patients with early- (N=24) and… CONTINUE READING


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