Hippocampal lesions produce both nongraded and temporally graded retrograde amnesia in the same rat.

@article{Winocur2013HippocampalLP,
  title={Hippocampal lesions produce both nongraded and temporally graded retrograde amnesia in the same rat.},
  author={Gordon Winocur and Melanie J Sekeres and Malcolm A. Binns and Morris Moscovitch},
  journal={Hippocampus},
  year={2013},
  volume={23 5},
  pages={330-41}
}
Rats were administered contextual fear conditioning and trained on a water-maze, spatial memory task 28 days or 24 h before undergoing hippocampal lesion or control surgery. When tested postoperatively on both tasks, rats with hippocampal lesions exhibited retrograde amnesia for spatial memory at both delays but temporally graded retrograde amnesia for the contextual fear response. In demonstrating both types of retrograde amnesia in the same animals, the results parallel similar observations… CONTINUE READING