Hippocampal lesions prevent trace eyeblink conditioning in the freely moving rat.

@article{Weiss1999HippocampalLP,
  title={Hippocampal lesions prevent trace eyeblink conditioning in the freely moving rat.},
  author={Craig Weiss and Hans Bouwmeester and John M Power and John F. Disterhoft},
  journal={Behavioural brain research},
  year={1999},
  volume={99 2},
  pages={123-32}
}
The effect of hippocampal aspiration lesions on trace eyeblink conditioning was examined in young, freely-moving F1 hybrid rats (Fisher 344 x Brown Norway). Rats which received either bilateral neocortical or bilateral hippocampal aspiration lesions were compared with each other or with sham lesioned control rats. The rats were trained with a 250 ms tone conditioning stimulus (CS), a 250 ms stimulus free trace interval and a 100 ms corneal airpuff unconditioned stimulus (US). Rats with lesions… CONTINUE READING

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