Hippocampal interneurons are abnormal in schizophrenia.

  title={Hippocampal interneurons are abnormal in schizophrenia.},
  author={Christine Konradi and Changkook Yang and Eric I. Zimmerman and Kathryn M. Lohmann and Paul J Gresch and Harry Pantazopoulos and Sabina Berretta and Stephan Heckers},
  journal={Schizophrenia research},
  volume={131 1-3},
OBJECTIVE The cellular substrate of hippocampal dysfunction in schizophrenia remains unknown. We tested the hypothesis that hippocampal interneurons are abnormal in schizophrenia, but that the total number of hippocampal neurons in the pyramidal cell layer is normal. METHODS We collected whole hippocampal specimens of 13 subjects with schizophrenia and 20 matched healthy control subjects to study the number of all neurons, the somal volume of neurons, the number of somatostatin- and… CONTINUE READING