Hippocampal granule cells express glutamic acid decar☐ylase-67 after limbic seizures in the rat

@article{Schwarzer1995HippocampalGC,
  title={Hippocampal granule cells express glutamic acid decar☐ylase-67 after limbic seizures in the rat},
  author={Christoph Schwarzer and G. Sperk},
  journal={Neuroscience},
  year={1995},
  volume={69},
  pages={705-709}
}
Temporal lobe epilepsy is the most common form of epilepsy. Decreased GABA-ergic inhibition has been suggested as one cause of hyperexcitability. On the other hand, increased expression of glutamic acid decarboxylase, the rate-limiting enzyme of GABA synthesis, has been found in interneurons of the hippocampus in patients with temporal lobe epilepsy and in rats after kainic acid-induced limbic seizures, indicating increased GABA-ergic transmission. Here we report differential expression of two… Expand
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