Hippocampal epigenetic modification at the brain-derived neurotrophic factor gene induced by an enriched environment.

Abstract

Environmental enrichment is an experimental paradigm that increases brain-derived neurotrophic factor (BDNF) gene expression accompanied by neurogenesis in the hippocampus of rodents. In the present study, we investigated whether an enriched environment could cause epigenetic modification at the BDNF gene in the hippocampus of mice. Exposure to an enriched… (More)
DOI: 10.1002/hipo.20775

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