Hippocampal damage associated with prolonged and fatal stress in primates.

@article{Uno1989HippocampalDA,
  title={Hippocampal damage associated with prolonged and fatal stress in primates.},
  author={Hideo Uno and Ross P. Tarara and J. G. Else and Mbaruk Abdalla Suleman and Robert Morris Sapolsky},
  journal={The Journal of neuroscience : the official journal of the Society for Neuroscience},
  year={1989},
  volume={9 5},
  pages={1705-11}
}
Sustained exposure to glucocorticoids (GCs), adrenal hormones secreted during stress, can cause neural degeneration in the rat. This is particularly so in the hippocampus, a principal neural target site for GCs, in which GCs can exacerbate the rate of neuron death during normal aging, as well as the severity of neuronal damage after various neurological… CONTINUE READING