Hippocampal atrophy in temporal lobe epilepsy is correlated with limbic systems atrophy

@article{Dzel2005HippocampalAI,
  title={Hippocampal atrophy in temporal lobe epilepsy is correlated with limbic systems atrophy},
  author={Emrah D{\"u}zel and Kolja Schiltz and Thomas Solbach and Th. Peschel and Torsten Baldeweg and J. Kaufmann and A. Szentkuti and H. J. Heinze},
  journal={Journal of Neurology},
  year={2005},
  volume={253},
  pages={294-300}
}
Hippocampal sclerosis in temporal lobe epilepsy (TLE) is often associated with hippocampal atrophy. This study assessed whether such atrophy is correlated with loss of gray matter volume in other brain regions. In 16 patients with TLE and clear magnetic resonance imaging–based evidence of hippocampal sclerosis, hippocampal volumes were determined manually and the local gray matter (LGM) amount was estimated throughout the entire brain using voxel–based morphometry. Voxelwise correlations… CONTINUE READING

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