Hinokitiol, a tropolone derivative, inhibits mouse melanoma (B16-F10) cell migration and in vivo tumor formation.

@article{Huang2015HinokitiolAT,
  title={Hinokitiol, a tropolone derivative, inhibits mouse melanoma (B16-F10) cell migration and in vivo tumor formation.},
  author={Chien-Hsun Huang and Shing-Hwa Lu and Chao-Chien Chang and Philip A. Thomas and Thanasekaran Jayakumar and Joen-Rong Sheu},
  journal={European journal of pharmacology},
  year={2015},
  volume={746},
  pages={148-57}
}
Invasion and metastasis are the major causes of treatment failure in patients with cancer. Hinokitiol, a natural bioactive compound found in Chamacyparis taiwanensis, has been used in hair tonics, cosmetics, and food as an antimicrobial agent. In this study, we investigated the effects and possible mechanisms of action of hinokitiol on migration by the… CONTINUE READING