Hindbrain Rhombic Lip Is Comprised of Discrete Progenitor Cell Populations Allocated by Pax6

@article{Landsberg2005HindbrainRL,
  title={Hindbrain Rhombic Lip Is Comprised of Discrete Progenitor Cell Populations Allocated by Pax6},
  author={Rebecca L. Landsberg and Rajeshwar Awatramani and Nina L. Hunter and Anna F. Farago and H J Dipietrantonio and Carolyn I. Rodr{\'i}guez and Susan M Dymecki},
  journal={Neuron},
  year={2005},
  volume={48},
  pages={933-947}
}
The lower rhombic lip (LRL) is a germinal zone in the dorsal hindbrain productive of tangentially migrating neurons, streaming extramurally (mossy fiber neurons) or intramurally (climbing fiber neurons). Here we show that LRL territory, operationally defined by Wnt1 expression, is parceled into molecular subdomains predictive of cell fate. Progressing dorsoventrally, Lmx1a and Gdf7 expression identifies the primordium for hindbrain choroid plexus epithelial cells; Math1, for mossy fiber neurons… CONTINUE READING
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