Highly tunable elastomeric silk biomaterials.

@article{Partlow2014HighlyTE,
  title={Highly tunable elastomeric silk biomaterials.},
  author={Benjamin P. Partlow and Craig Hanna and Jelena Rnjak-Kovacina and Jodie E. Moreau and Matthew B. Applegate and Kelly Ann Burke and Benedetto Marelli and Alexander N. Mitropoulos and Fiorenzo G Omenetto and David L Kaplan},
  journal={Advanced functional materials},
  year={2014},
  volume={24 29},
  pages={
          4615-4624
        }
}
Elastomeric, fully degradable and biocompatible biomaterials are rare, with current options presenting significant limitations in terms of ease of functionalization and tunable mechanical and degradation properties. We report a new method for covalently crosslinking tyrosine residues in silk proteins, via horseradish peroxidase and hydrogen peroxide, to generate highly elastic hydrogels with tunable properties. The tunable mechanical properties, gelation kinetics and swelling properties of… CONTINUE READING
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