Highly sensitive proximity mediated immunoassay reveals HER2 status conversion in the circulating tumor cells of metastatic breast cancer patients

@inproceedings{Kim2011HighlySP,
  title={Highly sensitive proximity mediated immunoassay reveals HER2 status conversion in the circulating tumor cells of metastatic breast cancer patients},
  author={Phillip S Kim and Xinjun Liu and Tani Ann Lee and Limin Liu and Robert Barham and Richard Kirkland and Glen Leesman and Anne Kuller and Belen Ybarrondo and S E Ng and Sharat Singh},
  booktitle={Proteome Science},
  year={2011}
}
The clinical benefits associated with targeted oncology agents are generally limited to subsets of patients. Even with favorable biomarker profiles, many patients do not respond or acquire resistance. Existing technologies are ineffective for treatment monitoring as they provide only static and limited information and require substantial amounts of tissue. Therefore, there is an urgent need to develop methods that can profile potential therapeutic targets with limited clinical specimens during… CONTINUE READING
Related Discussions
This paper has been referenced on Twitter 2 times. VIEW TWEETS

Citations

Publications citing this paper.
Showing 1-10 of 20 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 62 references

Kinetics and Mechanism of Action of Glucose Oxidase.

The Journal of biological chemistry • 1964
View 9 Excerpts
Highly Influenced

Detection and HER2 expression of circulating tumor cells: prospective monitoring in breast cancer patients treated in the neoadjuvant GeparQuattro trial.

Clinical cancer research : an official journal of the American Association for Cancer Research • 2010
View 2 Excerpts

Similar Papers

Loading similar papers…