Highly regioselective synthesis of benz[a]anthracene derivatives via a Pd-catalyzed tandem C-H activation/biscyclization reaction.

Abstract

A palladium-catalyzed tandem C-H activation/biscyclization reaction of propargylic carbonates with terminal alkynes was determined, which allowed the tetracyclic benz[a]anthracene framework to be constructed with high regioselectivity. A possible mechanism for this tandem C-H activation/biscyclization process was discussed.

DOI: 10.1021/jo802712n

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Cite this paper

@article{Ren2009HighlyRS, title={Highly regioselective synthesis of benz[a]anthracene derivatives via a Pd-catalyzed tandem C-H activation/biscyclization reaction.}, author={Zhi-hui Ren and Zheng-Hui Guan and Yong-Min Liang}, journal={The Journal of organic chemistry}, year={2009}, volume={74 8}, pages={3145-7} }