Highly purified eicosapentaenoic acid treatment improves nonalcoholic steatohepatitis.

@article{Tanaka2008HighlyPE,
  title={Highly purified eicosapentaenoic acid treatment improves nonalcoholic steatohepatitis.},
  author={Naoki Tanaka and Kenji Sano and Akira Horiuchi and Eiji Tanaka and Kendo Kiyosawa and Toshifumi Aoyama},
  journal={Journal of clinical gastroenterology},
  year={2008},
  volume={42 4},
  pages={413-8}
}
Recent studies have demonstrated that n-3 polyunsaturated fatty acids ameliorate nonalcoholic fatty liver disease. Although eicosapentaenoic acid (EPA), one of the major components of n-3 polyunsaturated fatty acids, is widely used as an antilipidemic agent, its single efficacy for nonalcoholic steatohepatitis (NASH) remains unclear. As such, we aimed to evaluate the efficacy and safety of EPA on 23 biopsy-proven NASH patients in a pilot trial. Highly purified EPA (2700 mg/d) was administered… CONTINUE READING
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