Highly potent anti-human GPVI monoclonal antibodies derived from GPVI knockout mouse immunization.

Abstract

Recent progress in the understanding of thrombus formation has suggested an important role for glycoprotein (GP) VI in this process. To clarify the exact role in detail, it is necessary to use specific, high affinity inhibitory antibodies. However, possibly due to the conserved structure of GPVI among species, it has been difficult to obtain potent… (More)

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@article{Matsumoto2007HighlyPA, title={Highly potent anti-human GPVI monoclonal antibodies derived from GPVI knockout mouse immunization.}, author={Yutaka Matsumoto and Hisao Takizawa and Xiaoqi Dr Gong and Sang N. Le and Simon Lockyer and Keiji Okuyama and Michinori Tanaka and Masuhiro Yoshitake and Narendra N. Tandon and Junichi Kambayashi}, journal={Thrombosis research}, year={2007}, volume={119 3}, pages={319-29} }