Highly penetrant hereditary cancer syndromes

@article{Nagy2004HighlyPH,
  title={Highly penetrant hereditary cancer syndromes},
  author={Rebecca S. Nagy and Kevin Sweet and Charis Eng},
  journal={Oncogene},
  year={2004},
  volume={23},
  pages={6445-6470}
}
The past two decades have brought many important advances in our understanding of the hereditary susceptibility to cancer. Approximately 5–10% of all cancers are inherited, the majority in an autosomal dominant manner with incomplete penetrance. While this is a small fraction of the overall cancer burden worldwide, the molecular genetic discoveries that have resulted from the study of families with heritable cancer have not only changed the way these families are counselled and managed, but… CONTINUE READING
103 Citations
41 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 103 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 41 references

Q

  • ER Maher, JR Yates, +4 authors MA. Ferguson-Smith
  • J. Med., 77, 1151–1163.
  • 1990
Highly Influential
4 Excerpts

Genetic Disorders of Endocrine Neoplasia Vol

  • S Chandrasekharappa, B. Teh
  • 28. Dahia, PLM and Eng, C (eds). Front Horm Res…
  • 2001
Highly Influential
3 Excerpts

Molecular Genetics of Cancer Cowell J (ed)

  • C. Eng
  • BIOS Scientific Publishers Ltd: Oxford, pp 171…
  • 2001
Highly Influential
4 Excerpts

Rev

  • C. Eng
  • Endocrinol. Metab. Dis., 1, 283–290.
  • 2000
Highly Influential
4 Excerpts

GeneReviews at Gene Tests: Medical Information Resource (database online). Copyright, University of Washington: Seattle, 1997–2004

  • C Soloman, Burt R. In
  • Available at http://www.genetests.org (Updated
  • 2004

Am

  • XP Zhou, KA Waite, +13 authors C. Eng
  • J. Hum. Genet., 73, 404–411.
  • 2003

Curr

  • A Woods, SR Johnstone, +7 authors D. Carling
  • Biol., 13, 2004–2008.
  • 2003

Cancer Epidemiol

  • D Thompson, D. Easton
  • Biomarkers Prev., 11, 329–336.
  • 2002
1 Excerpt

Hum

  • XP Zhou, S Kuismanen, M Nyström-Lahti, P Peltomaki, C. Eng
  • Mol. Genet., 11, 445–450.
  • 2002

Similar Papers

Loading similar papers…